Pharmacokinetics and Repolarization Effects of Intravenous and Transdermal Granisetron
نویسندگان
چکیده
منابع مشابه
Pharmacokinetics and repolarization effects of intravenous and transdermal granisetron.
PURPOSE The need for greater clarity about the effects of 5-HT(3) receptor antagonists on cardiac repolarization is apparent in the changing product labeling across this therapeutic class. This study assessed the repolarization effects of granisetron, a 5-HT(3) receptor antagonist antiemetic, administered intravenously and by a granisetron transdermal system (GTDS). EXPERIMENTAL DESIGN In a p...
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ژورنال
عنوان ژورنال: Clinical Cancer Research
سال: 2012
ISSN: 1078-0432,1557-3265
DOI: 10.1158/1078-0432.ccr-11-2785